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Targeted Intermediates of Eudesmic Acid: Synthesis and X-ray Investigations

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Targeted Intermediates of Eudesmic Acid: Synthesis and X-ray Investigations


Olimova M.I. | Okmanov R. Ya. | Elmuradov B. Zh.

https://doi.org/10.31142/ijtsrd2417



Olimova M.I. | Okmanov R. Ya. | Elmuradov B. Zh. "Targeted Intermediates of Eudesmic Acid: Synthesis and X-ray Investigations" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-1 | Issue-6, October 2017, pp.176-181, URL: https://www.ijtsrd.com/papers/ijtsrd2417.pdf

it was carried out synthesis of esters and their dinitro derivatives of 3,4,5-trimethoxybenzoic (eudesmic) acid. Esterification of eudesmic acid carried out n absolute methanol or ethanol and corresponding methyl and ethyl 3,4,5-trimethoxybenzoates (2, 3) have been synthesized in good yields. It was revealed that nitration of these esters gives only dinitro products. The structure of the synthesized compounds of the methyl and ethyl 2,6-dinitro-3,4,5-trimethoxybenzoates (4, 5) was determined by X-ray diffraction analysis (XRD). In the asymmetric part of the crystal structures of 4, 5 one and two molecules are observed, respectively. In crystalline structures a flat nitro groups and carboxylic groups do not participate in the conjugation with aromatic rings. In the crystal structure of 4, an intermolecular C8-H...O9 hydrogen bond is observed, these H bonds link the molecules along the [010] axis. In the crystal structure of 5, intermolecular C9B-H...O4A and C10B-H...O8A hydrogen bonds form chains along the [011] axis. The formed chains are cross linked by the intermolecular C9B-H...O5A hydrogen bonds.

synthesis; methyl and ethyl 3,4,5-trimethoxybenzoates; methyl and ethyl 2,6-dinitro-3,4,5-trimethoxybenzoates; esterification; nitration; X-ray diffraction analysis.


IJTSRD2417
Volume-1 | Issue-6, October 2017
176-181
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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